12 May 2017
Systematic review: pre- and post-operative prognostic value of cardiopulmonary exercise testing in liver transplant candidates
Interesting literature review on the Alimentary Pharmacology and Therapeutic Journal focusing on the role of cardio pulmonary exercise test (CPET) in cirrhosis patients.
The prognostic value of CPET for pre-and post-transplant mortality is evaluated in patients with cirrhosis listed for liver transplantation. In particular, this review analyses whether CPET remained predictive after adjustment for liver disease severity.
This literature review shows that "patient's listed for liver transplant have significant functional limitations, with a weighted mean VO2 below the threshold level required for independent living. Although heterogeneity in study designs with respect to timing, CPET variables, and cut-off values precluded the determination of CPET mortality thresholds, the studies support CPET as an objective and independent predictor of pre- and post-transplant mortality".
The article details are the following:
- Title: "Systematic review: pre- and post-operative prognostic value of cardiopulmonary exercise testing in liver transplant candidates"
- Authors: Ney M, Haykowsky MJ, Vandermeer B, Shah A, Ow M, Tandon P
- Published in: Aliment Pharmacol Ther. 2016 Oct;44(8):796-806
The study can be purchased at the following link: click here
Founded in 1980, COSMED is a privately owned company manufacturing Cardio Pulmonary and Metabolic Diagnostic Equipment. COSMED products include a full range of Spirometers, Pulmonary Function, Body Composition, Nutritional Assessment and Cardio Pulmonary Exercise systems, including Electrocardiographs, Ergometers and Assessment Software. COSMED solutions are aimed for either professional or medical use for many different applications like: Hospital, Clinics, Primary Care, University & Education in Human Physiology, Clinical Nutrition, Commercial Weight Management, Human Performance Centers, Sport Institutions and Health Club Industry. COSMED Headquarters are located in the province of Rome, Italy. COSMED has subsidiaries in the USA, China and Germany, and distributes its products internationally through a constantly growing distributor network covering more than 70 countries.