Different metabolic phases can be distinguished in critical illness, which influences nutritional treatment. Achieving optimal nutritional treatment during these phases in critically ill patients is challenging. The aim of this observational study is to describe measured resting energy expenditure (mREE) and feeding practices and tolerance during the acute and late phases of critical illness in...

Indirect calorimetry (IC)-guided nutrition might positively affect the clinical outcome of critically ill patients. The objective of this study is to assess the benefit of isocaloric nutrition guided by IC, compared to hypocaloric nutrition, for critically ill patients admitted to the intensive care unit (ICU). This systematic review and meta-analysis shows that patients treated with IC guided...

COVID-19 can rapidly progress into acute respiratory distress syndrome accompanied by multi-organ failure requiring invasive mechanical ventilation and critical care treatment. Nutritional therapy is a fundamental pillar in the management of hospitalized patients. It is broadly acknowledged that overfeeding and underfeeding of intensive care unit (ICU) patients are associated with increased morbidity...

Among other important risk factors for severe COVID-19 outcomes, obesity has emerged along with undernutrition-malnutrition as a strong predictor of disease risk and severity. Obesity-related excessive body fat may lead to respiratory, metabolic and immune derangements potentially favouring the onset of COVID-19 complications. Early after the onset of the COVID-19 pandemic, the European Society...